Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
AnimationComedyDramaSci-Fi & Fantasy
Creator: Joseph Bennett, Steve Hely
Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
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Common Side Effects is a 2025 animation and drama TV series from the United States created by Joseph Bennett and Steve Hely, starring Dave King, Emily Pendergast and Mike Judge. It first aired on February 2, 2025. The series has 2 seasons and 11 episodes on Adult Swim. Episodes run about 23 min, in English. Audiences rate it 8.5/10 from 360 votes — very well received.
Common Side Effects premiered on February 2, 2025.
Common Side Effects was created by Joseph Bennett and Steve Hely.
The main cast includes Dave King, Emily Pendergast, Mike Judge, Martha Kelly and Joseph Lee Anderson.
Common Side Effects has 2 seasons (11 episodes). Status: Returning Series.
No streaming service lists it for US yet. Add it to your watchlist and check back — availability updates regularly.
It holds an audience score of 8.5/10 from 360 ratings, so fans of animation and drama titles are its best audience. Read member reviews below or add your own.
Every episode's audience rating at a glance — find the best (and worst) episodes before you binge.
| E1 | E2 | E3 | E4 | E5 | E6 | E7 | E8 | E9 | E10 | |
|---|---|---|---|---|---|---|---|---|---|---|
| S1 | 7.7 | 7.5 | 7.9 | 7.6 | 7.1 | 7.5 | 7.4 | 7.2 | 7.6 | 7.9 |
| S2 | – |
9+ Awesome8+ Great7+ Good6+ Regular<6 Bad
mushroompharmaceutical industrydark comedyconspiracyadult animationgovernment conspiracymiracle curecomedy thrilleroptimistic